Thursday, June 19, 2025 | 11 AM ET
Presented by
James B. Hoying, PhD
The need for more informative and predictive cell and tissue models of human disease is driving technological innovations that leverage tissue biology concepts. This webinar will explore some of these concepts and avenues by which advanced human-relevant tissue models are being employed. An overview of cell sourcing for these models, including vascularization solutions, will be discussed while highlighting example solutions to readily build and deploy complex, vascularized tissues for human-relevant tissue modeling and regenerative therapies. As the advanced models are developed, new agile solutions for implementation help to fully realize their utility. Additionally, a regulatory framework around so called “New Approach Methodologies” (NAMs) using human-relevant models is emerging towards a larger goal of minimizing or replacing small animal testing in drug discovery.
The webinar will use the Zoom meeting platform and not the webinar platform. This will enable direct communication between the meeting participants. The total number of participants at this meeting will be limited to 100 individuals.
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Meet the Presenter
James B. Hoying, PhD
James (Jay) Hoying is a Partner and Chief Scientist at Advanced Solutions Life Sciences (ASLS) with more than 30 years of experience in basic and applied biological sciences with a focus in tissue biology, tissue vascularization, and tissue fabrication. At ASLS, he directs an active laboratory developing a variety of advanced, vascularized human tissue models and tissue therapeutics. Prior to joining ASLS, he was Professor and Chief of the Division of Cardiovascular Therapeutics at the Cardiovascular Innovation Institute (CII) where he developed a broad background in tissue
biology, cell therapeutics, and translation of discoveries to industry and the clinic. Dr. Hoying received his BA and MS degrees in Biology and Molecular Biology from Case Western Reserve University and his PhD in Cardiovascular Physiology, with an emphasis on the microcirculation, from the University of Arizona. Following his degree work, Dr. Hoying served as a New Investigator in the National Institutes of Health Program of Excellence in Molecular Biology of the Heart and Lung (POEMB). Dr. Hoying pioneered the use of native, intact microvascular elements in modeling vascularization and vascularizing tissues in vitro and in vivo; holding numerous patents related to vascularizing tissues and related cell-based therapies. He has published over 130 original research papers, reviews, and book chapters. He currently reviews grant proposals for the National Institutes of Health, the Veterans Administration, the National Science Foundation, the American Heart Association, and funding agencies around the world. Dr. Hoying serves on advisory committees for the state of New Hampshire and federal programs related to biotechnology and biomanufacturing.