No. This product is for research use only. Guidance for use of reagents in clinical cell transplantation procedures is governed by local Institutional Review Boards and regional Health Authorities. This product is manufactured in accordance with the principles for clinical trial material outlined in ICH Q7a. The document control system in place is in alignmentRead more about Is this product intended for use in diagnostic or therapeutic procedures?[…]
Application-specific formulations are pre-blended mixtures of purified collagenase and protease in optimal ratios for isolation of cells from a particular tissue and/or species. Currently, our CIzyme™ Collagenase AS and CIzyme™ Collagenase RI are our only two application-specific formulations.
There are two components to inactivation of the digestive enzymes commonly used for tissue dissociation. To inactivate protease activity, a serum-containing media or buffer is most effective. Buffers or media containing human serum albumin (HSA) are ineffective in suppressing protease activity, even at very high concentrations of protein (>10%). However, serum-containing buffers do not inhibitRead more about What is the best way to inactivate the enzymes when a digestion is complete?[…]