Do enzyme activities correlate with the effectiveness of cell isolation?

No and yes.

For poorly defined collagenase products, many isolators use these values as a guideline in selecting a specific lot of collagenase. These analyses are an unreliable predictor of successful cell isolation because the collagenase is often degraded by proteases during the manufacturing or manufacturing procedure. For defined collagenase products, if the manufacturer claims or shows data that the collagenase is intact and the protease activity is tightly controlled, then performing the appropriate enzymatic analysis can be a useful tool to predict the success of islet isolation.