Application Specific Formulations are pre-blended mixtures of purified collagenase and protease in optimal ratios for isolation of cells from a particular tissue and/or species. These formulations provide a recommended dose for use with an associated method. These effectiveness of these product to isolate specific cell types was demonstrated by several different laboratories. Currently, VitaCyte offer 3 application specific product to isolate rodent islets (CIzyme RI), human adipose stromal vascular fraction cells (CIzyme AS), and human islets (rCollagenase HI).