Successful human islet isolation and transplantation indicating the importance of class 1 collagenase and collagen degradation activity assay. by Jessica Helweg | Jan 8, 2019 A. N. Balamurugan, Andrew G. Breite, Takayuki Anazawa, Gopalakrishnan Loganathan, Joshua J. Wilhelm, Klearchos K. Papas, Francis E. Dwulet, Robert C. McCarthy, Bernhard J. Hering. (2010). Successful human islet isolation and transplantation indicating the importance of class 1 collagenase and collagen degradation activity assay. Transplantation. 89(8): 954–961. doi: 10.1097/TP.0b013e3181d21e9a.